MZO-8 EM 2025 SOLVED ASSIGNMENT

Description

M.Sc. (Zoology) Programme (MSCZOO)

Valid from 1st January, 2025 to 31st December, 2025

ASSIGNMENT
Course Code: MZO-008
Course title :Immunology

Assignment Code: MZO-008/TMA/2025

Note: Attempt all questions. The marks for each question are indicated against it.

1. a) What is IgM antibody. Discuss the functional importance of IgM.
2. b) Explain the concept of antigens and their classification as foreign or self antigens

2.. Differentiate between the following pairs of terms:

1. a) Classical Pathway and Alternative Pathway of complement activation
2. b) B cell receptor (BCR) and T cell receptor (TCR)
3. c) Active Immunization and Passive Immunization
4. d) Primary Immunodeficiency (PID) and Secondary Immunodeficiency
5. Write short notes on the following:
6. a) Ouchterlony Double Diffusion
7. b) Superantigens
8. c) Anaphylaxis
9. d) Immunosuppressive Therapy

4.a)  Define the term “chimeric antibodies” and discuss their applications.

1. b) Explain Edward Jenner contributed to the development of vaccines?
2. Describe the role of the bone marrow in the immune system, focusing on its structure and the process of hematopoiesis.

6.a)  Define autoimmunity and discuss its role in immune system dysfunction.

1. b) Explain how Gell and Coombs classified hypersensitivity reactions.

7.a)  Describe the process of complement-induced lysis through MAC formation.

1. b) Briefly describe the autocrine, paracrine, and endocrine functions of cytokines

8.a)  Discuss the pathways for processing both endogenous and exogenous antigens.

b.)  Explain the peptide-binding properties of Class I and II MHC molecules with a suitable diagram.

9. a) Discuss the flow cytometry principles and its components.
10. b) Explain the DOT ELISA techniques and their working principles.
11. Explain the importance of donor and recipient matching in transplantation immunology, focusing on the role of human leukocyte antigen (HLA) typing and its impact on reducing graft rejection.