MBC-8 EM 2025-26 SOLVED ASSIGNMENT

Description

Masters Degree in BIOCHEMISTRY (MSCBCH)

Course code: MBC-008
Course title: GENETICS AND EVOLUTIONARY BIOLOGY
(Valid from 1st July, 2025 to 31stDecember, 2026)

Note: Attempt all questions.The marks for each question are indicated against it. For any question worth 2 marks, the word limit is 50 words, for 5 marks question it is 100 words; and for 10 marks it is 250-300 words.

PART-(A)Maximum marks: 50

1 What are model organisms, and why are they important in biological research? Give characteristics of any two-model organism

2 (a) Describe how the behaviour of chromosomes at meiosis explains the law of independent assortment.

(b) Describe epistatic and non-epistatic gene interactions.

3 Explain non-mendalian inheritance with suitable examples.

4 (a) Explain how centromere is mapped with respect to a close by gene in Neurospora crassa.

(b) Explain cis- trans test of allelism (complementation test).

5 Explain with suitable examples chromosomal and environmental sex determination mechanisms.

PART-(B) Maximum marks: 50

6(a) Explain the significance of studying development biology.

(b) Differentiate between spermatogenesis and oogenesis.

7(a) Write brief note on the characteristics and importance of Hox genes.

(b) What are maternal determinants? Discuss their role in development of Drosophila.

8(a) Discuss the pedigree of an autosomal dominant trait. Name two human diseases with autosomal dominant inheritance.

(b) Explain the Lederberg and Tatum experiment and its inference.