MFN-2 2024-25 SOLVED ASSIGNMENT

Description

ASSIGNMENT -2
TMA-2
Nutritional Biochemistry
Course Code: MFN-002
Assignment Code: MFN-002/AST-2/TMA-2/24-25

Maximum Marks:100
This assignment is based on Units 1 – 12 of the MFN-002 Course
Section A –Descriptive Questions
There are ten questions in this part. Answer all questions.
1.
a) What is stero-isomerism? Explain giving an example.
b) What are polysaccharides? What are its types? Explain giving examples.
2.
a)Give the classification of lipids based on the chemical structure.
(80 Marks)
(3)
(5)
b) What is hydrogenation? What are the harmful health effects of partial hydrogenation
of fats?
c) Give the general structure of amino acid with one example each of polar, non-polar,
acidic and basic amino acids.
3.
4.
5.
6.
7.
8.
9.
a) How will you classify Vitamins based on their solubility?
b) Briefly explain the mechanism of enzyme action.
c) Differentiate between competitive and non-competitive enzyme inhibition.
a) Explain the process of carbohydrate digestion in our body.
b) What is the role of pancreas in digestion?
a) Briefly explain how blood glucose level is regulated in the body?
b) What is the net production of ATP when one molecule of glucose is converted to
pyruvic acid?
c) Briefly explain the components of electron transport chain.
a) What is the site for the synthesis of fatty acids? Explain giving the reactions involved
in the de-novo synthesis of fatty acids.
b) Define Lipoprotein and apolipoprotein with suitable examples.
a) What are Ketogenic and Glucogenic amino acids? Discuss their fate in our body.
b) What is the end product of purine degradation and what disease is caused because of
this?
a) Give the role of free radicals and antioxidants in lipid peroxidation.
b) Discuss the role of Vitamin K in the coagulation of blood.
c) Enumerate the physiological role of iron.
a) Illustrate the role of parathormone in calcium homeostasis.
b) Enumerate the different second messengers used in mechanism of hormone action.
10. a) List the common inborn errors due to protein metabolism. Explain briefly any two of
them.
b) Differentiate between sickle cell anaemia and thalasemia.
(2)
(2)
(4)
(2)
(4)
(2)
(4)
(4)
(2)
(2)
(4)
(1+4)
(3)
(2+3)
(3)
(3)
(3)
(2)
(3)
(5)
(5)
(3)
Section B – OTQ (Objective Type Questions) (20 Marks)
1. Explain the following in 2-3 sentences. Also give the structure wherever possible. (10)
a. Osazone reaction
b. Eicosanoids
c. Isoelectric pH
d. Holoenzyme
e. Pinocytosis
f. Ketosis
g. Cyclic AMP
h. Folate Trap
i. Transamination
j. Anaplerotic reactions

2. Name the defective enzyme in the following diseases: (5)
a) Tyrosinemia
b) Phenylketonurea
c) Alkaptonurea
d) Niemann-Pick-Disease
e) Von-Gierk’s Syndrome

3. Match the items in List I with items in List II : (5)

List I List II
I Calcitonin A Pineal
II Oxytocin B Pancreas
III Glucagon C Parathyroid
IV Glucocorticoids D Pituitary
V Epinephrine E Thyroid
F Adrenal Cortex
G Adrenal Medulla