Description
MANE–001: HUMAN GENETICS
Tutor Marked Assignment (TMA)
Course Code: MANE-001
Assignment Code: MANE-001/ASST/TMA/2024-2025
Total Marks: 100
Note: Attempt a total of five questions. All questions carry equal marks. The word limit for 20 marks
question is 500 words and for 10 marks question it is 250 words. Attempt at least two questions from
each section.
Section A
1. Define Human Genetics? Discuss briefly the different branches of Human Genetics. 20
2. What is inbreeding? Discuss different types of inbreeding in human populations. 20
3. Describe the structure and features of DNA. 20
4. What is Mitosis? Briefly comment on various stages of cell division with suitable diagrams. 20
5. Write short notes on any two of the following: 10+10
a). Hardy- Weinberg Law
b). Polymorphism
c). FISH
d). Y-linked inheritance
Section B
6. Discuss the concept of gene in the light of Beadle and Tautum’s work. 20
7. What is a Chromosomal aberration? Describe different types of chromosomal aberrations. 20
8. What is PTC? Describe the procedure for PTC tasting ability through serial dilution method. 20
9. Discuss different forms of DNA Polymorphisms. 20
10. Write short notes on any two of the following : 10+10
a). Polymerase Chain Reaction (PCR)
b). Hap Map Project
c). Ethical principles in genetic research
d). Phenylketonuria (PKU)
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