BBCCT-127 EM 2024 SOLVED ASSIGNMENT

Description

ASSIGNMENT
Immunology
Core Course in Biochemistry
Course Code: BBCCT-127
Assignment Code: BBCCT-127/TMA/2024
Maximum Marks: 100
——————————————————————————————————————
Note: Attempt all questions. The marks for each question are indicated against it. Write all
answers in your own words; do not copy from the course material.
PART-(A) (50)
1. Distinguish between the following:
a) primary lymphoid organs and secondary lymphoid organs
b) agranulocytes and granulocytes
(5+5=10)
2. a) How a pathogen is internalized? Explain with the help of diagram. (5)
b) Enlist and enumerate the steps for leukocyte extravasation? (5)
3. Discuss alternate pathway of complement activation. (10)
4. How following factors influence the immunogenicity?
a) Traits of Host
b) Traits of Immunogen
(5+5=10)
5. Describe Tonegawa and Hozumi experiment. (10)
PART-(B) (50)
6. Explain stages and steps of B-lymphocyte maturation. (10)
7. Give an overview of pathways of antigen processing and presentation. (10)
8. Discuss different types of CD4+ Helper T cells. (10)
9. Differentiate between the following:
i) TCR and Immunoglobulin
ii) Positive and Negative T-cell selection
(5+5 =10)
10. Describe the following:
a) IgE mediated hypersensitivity.
b) Active and Passive Immunization