Description
Assignment
GENE ORGANISATION, REPLICATION AND REPAIR
Course Code: BBCCT-117
Assignment code: BBCCT-117/TMA/2026
(Valid from 1st January, 2026 to 31st December, 2026)
Note: Attempt all questions. The marks for each question are indicated against it. For any question worth 2 marks, the word limit is 50 words, for 5 marks question it is 100 words; and for 10 marks it is 250-300 words.
PART-(A) Maximum marks: 50
1 Explain DNA melting, Tm and its significance.
2 Write a note on types of promoters in a prokaryotic gene.
3 What are the various functions of chromatin? How histone proteins help in chromatin compaction?
4 (a) Draw and label structure and parts of chromosome.
(b) Explain the chemistry behind phosphodiester bond formation
5 Differentiate between prokaryotic and eukaryotic DNA polymerases.
PART-(B) Maximum marks: 50
1 Describe the Holliday model for homologous recombination.
2 Explain the process of replication in prokaryotes.
3 Explain the integration of λ-phage DNA into bacterial genome.
4 (a) What is RNA editing?
(b) Write a short note on chloroplast inheritance.
5 (a) Explain the base excision repair mechanism with the help of a suitable diagram.
(b) What is xeroderma pigmentosum? Describe the cause of the disease.



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