BBCCT-123 EM 2024 SOLVED ASSIGNMENT

Description

ASSIGNMENT
GENE EXPRESSION AND REGULATION
Course Code: BBCCT-123
Assignment Code: BBCCT-123/TMA/2024
Maximum Marks: 100
Answer all the questions given below. All Questions carry equal marks.
1. A) What are promoter sequences. Explain their significance in prokaryotic transcription.
B) Draw and explain the structural organization of a gene. (5+5) 10
2. A) Describe transcription bubble formation in prokaryotes. 5
B) What are inhibitors? List prokaryotic transcription inhibitors and describe any two of
them. 5
3. Write a note on RNA polymerase I mediated transcription in eukaryotes. 10

4. A) Give a comparative account on eukaryotic and prokaryotic transcription. 5
B) Explain the mechanism of mRNA capping and its biological significance. 5

5. A) Define mRNA splicing. Describe spliceosome mediated splicing. 5
B) Differentiate between alternative and trans splicing. 5
6. A) Elaborate homing and retrohoming mechanisms. 5
B) Illustrate the structure of transfer RNA and its functions. 5

7. What is genetic code? Explain Khorana experimental contributions in understanding
genetic code. Give the salient features of genetic code. 10

8. Write a detailed note on eukaryotic translation. 10

9. A) What is antibiotic? Give the details of antibiotics used in medicine. 5
B) Differentiate between negative and positive gene regulation. 5

10. A) Explain how SOS response help DNA in repairing the damage caused by
external agents. 5
B) Describe the synthesis and function of miRNA