BBCCT-113 EM 2024 SOLVED ASSIGNMENT

Description

ASSIGNMENT
Metabolism of
Amino Acids and Nucleotides
Core Course in Biochemistry
Course Code: BBCCT-113
Assignment Code: BBCCT-113/TMA/2024
Maximum Marks: 100
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Note: Attempt all questions. The marks for each question are indicated against it. Write all
answers in your own words; do not copy from the course material.
PART-(A) (50)
1. Draw nitrogen cycle and explain major stages of the cycle. (10)
2. Discuss the catabolic role of amino acids that are converted to succiny-CoA. (10)
3.
4.
Explain the following disorders:
a) Phenyketonuria
b) Methylmalonyl aciduria
Discuss the biosynthesis of the following:
a) Aromatic Amino Acid Family
b) Serine Family
(5+5=10)
(5+5=10)
5. Describe Heme biosynthesis. (10)
PART-(B) (50)
6. How pyrimidine nucleotides (UMP) are synthesized de novo? (10)
7.
a) Explain the salvage pathway of purine nucleotides synthesis.
b) Describe the regulation of RNR?
(5)
(5)
8. Describe the degradation of purine nucleotides. (10)
9. Discuss organ specific metabolic profile of muscle.
(10)
10. Describe diagnosis and symptoms of:
i) Lesch-Nyhan Syndrome
ii) Gout